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The benefit of an oral medicine

I like taking my first pill when I wake up, and my second pill after dinner. I’m glad that it doesn’t matter if I take it on an empty stomach or not. —Patient being treated with TAVALISSE

TAVALISSE has no dietary restrictions

How should I take TAVALISSE?

Your healthcare provider will find the right treatment schedule for you. They may decide to adjust the dose of your pills or how often you take them based on your response to treatment. Be sure to take TAVALISSE exactly as prescribed.

daily

twice dailyORAL MEDICINE

food

take with orWIThout food

How often will my healthcare provider monitor my response?

Your healthcare provider will check your complete blood count (which includes platelets, red blood cells, and white blood cells), liver function, and blood pressure. They may change your dose depending on your test results.

How long should I take TAVALISSE?

TAVALISSE needs to be taken every day as prescribed, even if you start to feel better. This is important to manage your platelet counts.

Your healthcare provider will tell you to keep taking TAVALISSE as long as it works to maintain your platelet counts and you continue to respond to therapy.

If changes are needed to your TAVALISSE dose, your healthcare provider will let you know.

What else should I know about taking TAVALISSE?

If you miss a dose of TAVALISSE, take your next dose at its regularly scheduled time. If you take too much TAVALISSE, call your healthcare provider right away or go to the nearest hospital emergency room right away.


Fit TAVALISSE into your lifestyle

Tips for more successful treatment

It’s important that you take TAVALISSE every day as prescribed by your healthcare provider. Creating a daily routine will help make TAVALISSE a regular part of your lifestyle. Here are some tips to get you started. Find a method that works best for you.

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TAKE ADVANTAGEOF TECHNOLOGY

Set a daily alarm on your cell phone or a calendar reminder to alert you when it’s time to take your medicine.

There are also a number of apps available to help you stay on track. Pick one that works for you.

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cOMBINE WITHDAILY ACTIVITIES

You can tie taking your medicine twice a day to your current routine.

For example, you could tie it to brushing your teeth in the morning and before you go to bed, or you could tie it to eating breakfast and dinner.

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BUILD ASUPPORT TEAM

Friends and family may be able to help remind you to take your medicine and stay on track with your treatment plan.

Talk with them and make a plan that will work for you.

Fitting TAVALISSE into Your Lifestyle

To get the benefit of your medication, you need to take it as prescribed. Therefore, it’s important to have a medication with dosing flexibility and convenience—that you can take with or without food. Watch this video to get tips from advanced nurse practitioner Charina Toste on how to fit TAVALISSE into your lifestyle.

Important Safety Information

What is TAVALISSE?

TAVALISSE is a prescription medication used to treat adults with low platelet counts due to chronic immune thrombocytopenia (ITP) when a prior treatment for ITP has not worked well enough. It is not known if TAVALISSE is safe and effective in children.

What is the most important information I should know about TAVALISSE?

TAVALISSE can cause serious side effects including: 

  • High blood pressure (hypertension). New or worsening high blood pressure is common in people treated with TAVALISSE and can be severe. Your healthcare provider will check your blood pressure regularly during treatment with TAVALISSE. If needed, your healthcare provider may start you on blood pressure medicine or change your current medicine to treat your blood pressure. Tell your healthcare provider if you get headaches, confusion, dizziness, chest pain, or shortness of breath.
  • Liver problems. Changes in liver function blood tests are common with TAVALISSE. Liver problems may occur and can be severe. Your healthcare provider will regularly do blood tests to check how well your liver is working during treatment with TAVALISSE.
  • Diarrhea. Diarrhea is common in people treated with TAVALISSE and can be severe. Tell your healthcare provider if you get diarrhea during treatment with TAVALISSE. Your healthcare provider may recommend changes in your diet, drinking more water, or medicine to limit these symptoms.
  • Decreases in white blood cell count (neutropenia). Decreases in your white blood cell count are common with TAVALISSE and can be severe. This may increase your risk for infection, including serious infections. Your healthcare provider will regularly do blood tests to check your white blood cell counts.

Your healthcare provider may change your dose, temporarily stop, or permanently stop treatment with TAVALISSE if you have side effects.

What do I need to discuss with my healthcare provider before taking TAVALISSE?

Before you take TAVALISSE, tell your healthcare provider about all of your medical conditions, including if you: 

  • have high blood pressure
  • have liver problems
  • are pregnant or plan to become pregnant. TAVALISSE can harm your unborn baby.
    • Your healthcare provider will check if you are pregnant before starting treatment with TAVALISSE.
    • Females who can become pregnant should use effective birth control during treatment with TAVALISSE and for at least 1 month after the last dose.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking TAVALISSE with certain other medicines may affect how the other medicines work or how TAVALISSE works. 

What are the possible side effects of TAVALISSE?

The most common side effects of TAVALISSE include:

  • Nausea, rash, dizziness, tiredness, respiratory infection, chest pain, and stomach (abdomen) pain.

These are not all the side effects of TAVALISSE. For more information, ask your healthcare provider or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA, at 1-800-FDA-1088

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Important Safety Information

What is TAVALISSE?

TAVALISSE is a prescription medication used to treat adults with low platelet counts due to chronic immune thrombocytopenia (ITP) when a prior treatment for ITP has not worked well enough. It is not known if TAVALISSE is safe and effective in children.

What is the most important information I should know about TAVALISSE?

TAVALISSE can cause serious side effects including:

  • High blood pressure (hypertension). New or worsening high blood pressure is common in people treated with TAVALISSE and can be severe. Your healthcare provider will check your blood pressure regularly during treatment with TAVALISSE. If needed, your healthcare provider may start you on blood pressure medicine or change your current medicine to treat your blood pressure. Tell your healthcare provider if you get headaches, confusion, dizziness, chest pain, or shortness of breath.

September is ITP Awareness month

Join Rigel in helping to raise awareness of immune thrombocytopenia (ITP) and showing support for ITP patients, care partners, and healthcare providers

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